Friday, November 15, 2024

Newborn Jaundice: Causes, Symptoms, Treatment and Prevention- Wellsun Medicity

 

Understanding Newborn Jaundice Or (Neonatal hyperbilirubinemia)

Newborn jaundice occurs when a baby's skin and eyes appear yellow due to elevated bilirubin levels. Typically, it resolves as the liver matures and the baby begins to feed, generally clearing up within 2 to 3 weeks. However, if jaundice persists, it may indicate an underlying issue. High bilirubin levels pose a risk of brain damage in infants.

Causes and types

Bilirubin is a yellow pigment that forms when red blood cells break down. In older infants and adults, the liver efficiently processes bilirubin, allowing it to move through the digestive system. However, a newborn's liver is still developing and may not be ready to handle this process effectively.

There are two main types of newborn jaundice: physiological and pathological. Physiological jaundice is the most common, making up about 75% of cases. It occurs when a baby's body can't clear bilirubin quickly enough, usually showing up a few days after birth and resolving on its own within a few weeks as the liver matures and red blood cell breakdown slows down.

Pathological jaundice, on the other hand, indicates an underlying issue that affects the baby's ability to filter out bilirubin and may appear within the first 24 hours after birth.

                                                                                                                                                                                                                                                     

Risk factors

These include:

·         premature birth,

·         history of newborn jaundice in siblings,

·         being male assigned at birth (MAAB),

 

Diagnosis

While the yellow color in a baby confirms that they have jaundice, more tests might be needed to see how serious it is. Babies with jaundice usually get a blood test to measure the amount of bilirubin in their blood. Other tests may also be done to check for any underlying problems, including a complete blood count (CBC), blood type, and Rh incompatibility. Additionally, a Coombs test might be performed to look for antibodies that indicate a higher risk of red blood cell breakdown.

Treatment

Mild jaundice usually goes away on its own as a baby's liver matures, and feeding them frequently (at least 8 times a day) can help them get rid of bilirubin. If jaundice is more severe, other treatments may be needed. One common and effective treatment is phototherapy, which uses special blue lights to help break down bilirubin. During phototherapy, the baby lies on a special bed under the light, wearing just a diaper and protective goggles. Sometimes, a fiber-optic blanket is used too. In very serious cases, an exchange transfusion might be required, where the baby receives small amounts of healthy donor blood to replace damaged blood and lower bilirubin levels. If there’s an underlying issue causing the jaundice, that will need to be treated as well.

Prevention:

You can't prevent physiological jaundice, but you can lower the chances of it happening by feeding your newborn often. This helps them get rid of bilirubin faster. If you or your doctor suspect there might be an underlying issue causing jaundice, there are tests available to check for this so that you or your baby can get any necessary preventive treatment.

 

Consult with Dr.Ankit Pachauri  at wellsun medicity discuss your risk factors and develop a personalized plan to reduce your risk.

Wellsun Medicity Multispecialty Hospital

Dr.Ankit Pachauri

MBBS, (KGMU)MD Pediatrics (KGMU) - Pediatrics

www.wellsunmedicity.com

 


Thursday, November 14, 2024

Recurrent pregnancy loss | Nature Reviews Disease Primers-Wellsun Medicity Hospital

 

Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more consecutive miscarriages prior to 20 weeks of gestation. It can result from various factors, including genetic, anatomical, hormonal, autoimmune, or chromosomal abnormalities, and can cause significant emotional distress for affected individuals. Evaluating the underlying causes is crucial for managing RPL and improving the chances of a successful pregnancy in the future.

What causes recurrent pregnancy loss?

Recurrent pregnancy loss can be caused by a variety of factors, including genetic abnormalities in either parent, anatomical issues such as uterine abnormalities or scarring, hormonal imbalances (like thyroid disorders or polycystic ovary syndrome), autoimmune conditions (such as antiphospholipid syndrome), and infections. Additionally, lifestyle factors, maternal age, and certain chronic health conditions can also contribute to the risk of miscarriage. Identifying the specific cause in each case is essential for appropriate management and treatment options.

What tests are done for couples with recurrent pregnancy loss?

Couples experiencing recurrent pregnancy loss may undergo a variety of tests to identify potential underlying causes. Common evaluations include karyotyping (genetic testing) for both partners to detect chromosomal abnormalities, ultrasound to assess uterine structure for abnormalities or fibroids, blood tests to check hormone levels (like progesterone and thyroid hormones), and tests for blood clotting disorders (such as antiphospholipid syndrome). Additionally, genetic screening of the fetal tissue may be performed after a loss, and screening for infections or autoimmune conditions may also be considered. A comprehensive approach helps to tailor the management plan effectively.

What treatment is available for recurrent pregnancy loss?

Treatment for recurrent pregnancy loss depends on the underlying cause identified through testing. Options may include hormonal therapies to address imbalances, surgical interventions to correct anatomical issues in the uterus, and management of chronic conditions like diabetes or thyroid disorders. For couples with genetic issues, preimplantation genetic testing may be offered during in vitro fertilization (IVF). If autoimmune disorders are implicated, medications such as corticosteroids or anticoagulants may be prescribed. Lifestyle modifications, including proper nutrition,

 weight management, and quitting smoking or reducing alcohol intake, can also be beneficial. Each treatment plan is individualized based on the specific factors contributing to the losses.

Unexplained recurrent pregnancy loss,

Unexplained recurrent pregnancy loss (RPL) occurs when couples experience multiple miscarriages without a clear medical explanation despite thorough evaluation and testing. Approximately 50-70% of RPL cases fall into this category, making it particularly challenging for affected couples. Potential management strategies include close monitoring during subsequent pregnancies, the use of progesterone supplements, low-dose aspirin, or anticoagulants for those with suspected clotting issues, and lifestyle modifications. Psychological support and counseling may also be beneficial, as the emotional toll of recurrent losses can be significant. While no definitive treatment guarantees success in unexplained cases, many couples eventually achieve a successful pregnancy.


Consult wellsun medicity discuss your risk factors and develop a personalized plan to reduce your risk.

Wellsun Medicity Multispecialty Hospital
www.wellsunmedicity.com
Dr Karuna Singh
MBBS, MD (OBG), DNB, FRM - Gynecologist


Call:  +91-8810787432ore 

 

 



Monday, November 11, 2024

Knee Replacement Surgery: Overview & Recovery Process-wellsun medicity hospital

 

Knee Replacement Surgery: Overview & Recovery Process

Knee surgery encompasses various surgical procedures aimed at addressing knee joint issues, such as injuries, arthritis, or degenerative conditions. The most common types include knee replacement (total or partial), arthroscopy (a minimally invasive procedure for diagnosing and treating joint problems), and ligament reconstruction (such as ACL reconstruction). During these procedures, surgeons may remove damaged cartilage, realign bones, or replace parts of the joint to alleviate pain and restore function. Recovery typically involves physical therapy, pain management, and gradual return to activities, with the goal of enhancing mobility and improving quality of life.

Knee Replacement Surgery.

Knee replacement surgery, also known as knee arthroplasty, is a surgical procedure, in which damaged or worn surfaces of the knee joint are replaced with artificial components,

often made of metal and plastic. This surgery is typically performed to relieve pain, restore function, and improve quality of life in individuals with severe knee arthritis, injury, or degeneration that has not responded to conservative treatments. The surgery can be partial, replacing only one compartment of the knee, or total, replacing the entire joint. Following surgery, patients usually undergo rehabilitation to regain strength and mobility.


Why is Knee Replacement Performed?

Knee replacement surgery is performed for various reasons:

Pain Relief: When severe knee pain persists despite conservative treatments like medications, physical therapy, or assistive devices, it can greatly hinders daily activities. The goal of knee replacement is to alleviate chronic pain and enhance overall function.

Improved Mobility: A compromised knee joint can restrict movement, making walking, climbing stairs, and participating in daily activities challenging. This surgery aims to restore mobility and improve the ability to perform everyday tasks.

Joint Stability: Knee replacement can offer stability and support in cases of knee joint instability caused by ligament damage or severe arthritis.

Correction of Deformities: This surgery can correct deformities such as bowed legs or knock knees, helping to restore proper alignment and function.




Recovery Process

Recovery varies by procedure but often includes physical therapy to enhance strength and range of motion, with many patients experiencing significant improvement in quality of life post-surgery. 

More about Knee Replacement Surgery

Surgical Technique: Knee replacement surgery involves removing damaged joint surfaces and replacing them with artificial implants made of metal, plastic, or a combination of both. The surgery can be categorized as a total knee replacement, which addresses all three compartments of the knee, or a partial knee replacement, which focuses on a specific compartment.

Anesthesia: This procedure can be performed under general anesthesia, regional anesthesia (such as spinal or epidural), or a combination of local anesthesia and sedation. The choice of anesthesia is influenced by various factors, including patient preference and the surgeon’s advice.

Recovery and Rehabilitation: After surgery, you'll spend time in a recovery area before moving to a hospital room. Physical therapy and pain management techniques will begin to facilitate healing, restore strength, and improve range of motion. The length of your hospital stay and rehabilitation period will depend on individual circumstances.

Long-Term Outcomes: Knee replacement surgery generally boasts a high success rate for pain relief and functional improvement. Most patients report a significant decrease in knee pain, enhanced mobility, and an overall better quality of life.

Type of Knee Replacement:

1.Unicompartmental Knee Replacement (UKR): This procedure focuses on replacing one compartment of the knee (either the medial or lateral compartment), typically when arthritis is localized to just that area.

 2.Total Knee Replacement (TKR): In a cruciate-retaining total knee replacement, the entire knee joint is replaced, and the PCL is preserved, which aims to maintain the knee's natural kinematics and stability during movement. This type is often chosen for patients who have intact PCLs and do not have severe deformities or arthritis that would necessitate its removal.

3.which includes a cam and post mechanism that helps stabilize the knee during movement.

4.Revision Knee Replacement: When a previous knee replacement fails, a revision surgery may use a posterior-stabilized component for improved stability.

Consult Wellsun Medicity discuss your risk factors and develop a personalized plan to reduce your risk.

Wellsun Medicity Multispecialty Hospital 

Dr.SHANTANU SHARMA

MBBS,MS,(ORTHOPAEDICS) - ORTHOPAEDICS

www.wellsunmedicity.com

 


Thursday, November 7, 2024

Prostate Cancer Causes and Factors That Put You at Risk-wellsun medicity hospital

 

What is Prostate Cancer

Prostate cancer is a type of cancer that occurs in the prostate, a small walnut-shaped gland in males that produces seminal fluid, which nourishes and transports sperm. This cancer typically develops slowly and may initially be confined to the prostate gland, where it might not cause serious harm. However, some types can be aggressive and spread quickly.

Risk Factors

·         Several factors can increase the risk of developing prostate cancer, including:



·         Age: Risk increases with age, especially after 50.

·         Family History: Having a family history of prostate cancer can raise risk.

·         Race: African American men are at a higher risk than men of other races.

·         Genetic Factors: Certain inherited gene mutations (e.g., BRCA1 and BRCA2) may increase risk.

Symptoms

In its early stages, prostate cancer may not cause noticeable symptoms. As it progresses, symptoms may include:

·         Frequent urination, especially at night

·         Difficulty starting or stopping urination

·         Weak or interrupted urine flow

·         Painful urination or ejaculation

·         Blood in urine or semen

·         Pain in the lower back, hips, or pelvis

Diagnosis

Prostate cancer is typically diagnosed through:

Digital Rectal Exam (DRE): A physical exam where a doctor checks the prostate for abnormalities.

Prostate cancer is a type of cancer that occurs in the prostate, a small walnut-shaped gland in males that produces seminal fluid, which nourishes and transports sperm. This cancer typically develops slowly and may initially be confined to the prostate gland, where it might not cause serious harm. However, some types can be aggressive and spread quickly.

Risk Factors

·         Several factors can increase the risk of developing prostate cancer, including:

·         Age: Risk increases with age, especially after 50.

·         Family History: Having a family history of prostate cancer can raise risk.

·         Race: African American men are at a higher risk than men of other races.

·         Genetic Factors: Certain inherited gene mutations (e.g., BRCA1 and BRCA2) may increase risk.

Symptoms

In its early stages, prostate cancer may not cause noticeable symptoms. As it progresses, symptoms may include:

·         Frequent urination, especially at night

·         Difficulty starting or stopping urination

·         Weak or interrupted urine flow

·         Painful urination or ejaculation

·         Blood in urine or semen

·         Pain in the lower back, hips, or pelvis

·         Diagnosis

·         Prostate cancer is typically diagnosed through:

 

Digital Rectal Exam (DRE): A physical exam where a doctor checks the prostate for abnormalities.

Prostate-Specific Antigen (PSA) Test: A blood test that measures the level of PSA, a substance produced by the prostate, which can be elevated in men with prostate cancer.

Biopsy: If tests indicate cancer, a biopsy may be performed to confirm the diagnosis and determine the aggressiveness of the cancer.

Treatment

Treatment options vary depending on the stage of the cancer, the patient's overall health, and personal preferences, and may include:

·         Active Surveillance: Monitoring the cancer closely without immediate treatment.

·         Surgery: Prostatectomy (removal of the prostate) can be curative, especially in localized cancer.

·         Radiation Therapy: Targeting cancer cells with high-energy radiation.

·         Hormone Therapy: Reducing levels of male hormones that can fuel cancer growth.

·         Chemotherapy: Using drugs to kill cancer cells, typically reserved for advanced cases.

·         Immunotherapy: Using the body’s immune system to fight cancer.

Prognosis

The prognosis for prostate cancer varies widely. Many men diagnosed with early-stage prostate cancer may live for many years without it affecting their quality of life. Regular screening and early detection improve treatment outcomes significantly.

If you have any specific questions or need more detailed information, feel free to ask!

 Wellsun Medicity Multispecialty Hospital

www.wellsunmedicity.com

Dr. Neeraj Agarwal

MBBS (KGMU) MS General Surgeon

M.ch Urologist, Kidney Transplant Surgery   

Call:  +91-8810787432ore than 

Preeclampsia in pregnancy. Symptoms. Diagnosis. Treatment- wellsun medicity

 Preeclampsia in pregnancy

Preeclampsia is a pregnancy-related condition characterized by high blood pressure and damage to organs, often the kidneys and liver, typically occurring after the 20th week of gestation. It can lead to serious complications for both the mother and baby if not identified and managed properly. Symptoms may include swelling, protein in the urine, severe headaches, and visual disturbances, and the only definitive treatment is usually the delivery of the baby.


Preeclampsia can lead to various severe complications for the mother, including high blood pressure, organ damage (especially to the kidneys and liver), and increased risk of cardiovascular issues. It can also result in placental abruption, where the placenta if B.P is uncontrolled, detaches detaches from the uterus prematurely, leading to serious health risks for both mother and baby. In severe cases, it may progress to eclampsia, characterized by seizures. Long-term effects may include an increased risk of developing hypertension, cardiovascular disease, and renal issues later in life. Early identification and management are crucial to mitigate these risks.

Effects of preeclampsia on the mother,

At its most severe, preeclampsia can result in extremely high blood pressure and affect various organs, including the kidneys, liver, brain, and blood clotting system. If left untreated, it may lead to serious complications such as seizures, kidney and liver failure, clotting disorders, or even death. All types of preeclampsia require treatment. While it is challenging to predict who will develop the condition, certain women are at higher risk, including those experiencing their first pregnancy, those with a history of high blood pressure, those with a family history of the condition, those with diabetes, and those carrying multiple fetuses.

What are the symptoms of preeclampsia?

Symptoms of preeclampsia may include high blood pressure, protein in the urine, severe headaches, changes in vision (such as blurred vision or light sensitivity), abdominal pain (often under the ribs), swelling in the face and hands, sudden weight gain (often due to fluid retention), and decreased urine output. Some women may also experience nausea or vomiting. It is essential for pregnant individuals to be vigilant for these symptoms and communicate them to their healthcare provider, as early detection and management are crucial for the health of both mother and baby.

Effects of preeclampsia on the unborn baby.

Preeclampsia can have significant effects on the unborn baby, including restricted growth due to placental insufficiency, preterm birth, low birth weight, and increased risk of stillbirth. The condition can impair blood flow to the placenta, affecting the delivery of oxygen and nutrients necessary for healthy development. Additionally, babies born to mothers with preeclampsia may face a higher chance of complications after birth, such as respiratory distress syndrome and other health issues. Long-term, children born to mothers with preeclampsia may also be at a higher risk for cardiovascular problems later in life.

Diagnosis of preeclampsia,

Preeclampsia can have significant effects on the unborn baby, including restricted growth due to placental insufficiency, preterm birth, low birth weight, and increased risk of stillbirth. The condition can impair blood flow to the placenta, affecting the delivery of oxygen and nutrients necessary for healthy development. Additionally, babies born to mothers with preeclampsia may face a higher chance of complications after birth, such as respiratory distress syndrome and other health issues. Long-term, children born to mothers with preeclampsia may also be at a higher risk for cardiovascular problems later in life.

Treatment of preeclampsia,

Treatment of preeclampsia primarily involves close monitoring and management of symptoms, as the only definitive cure is delivery of the baby. Mild preeclampsia may be managed with lifestyle changes, such as bed rest and blood pressure monitoring, along with regular check-ups. In more severe cases, medications may be prescribed to lower blood pressure and prevent seizures, such as magnesium sulfate. If the condition worsens or poses risks to the mother or fetus, early delivery may be recommended, regardless of gestational age. Postpartum monitoring is also essential, as symptoms can persist after delivery.

Current preeclampsia research,

 

Current research on preeclampsia is focusing on understanding its underlying mechanisms, identifying biomarkers for early detection, and exploring potential therapeutic interventions. Studies are investigating the role of factors such as genetics, immune response, and placental development in the onset of preeclampsia. Research is also examining the use of medications like low-dose aspirin and calcium supplementation for prevention in high-risk populations. Additionally, there is growing interest in the long-term implications of preeclampsia for both mothers and children, prompting investigations into cardiovascular health and metabolic outcomes following pregnancy. Advances in technology, such as machine learning, are being applied to predict preeclampsia risk more accurately.

 

Consult wellsun medicity discuss your risk factors and develop a personalized plan to reduce your risk.

Wellsun Medicity Multispecialty Hospital 

www.wellsunmedicity.com

Dr Karuna Singh

MBBS, MD (OBG), DNB, FRM - Gynecologist

Call:  +91-8810787432ore 

Wednesday, November 6, 2024

Kidney stones - Symptoms, causes, types, and treatment-wellsun medicity

 What is Kidney

A kidney stone is a hard object that is made from chemicals in the urine. There are four types of kidney stones: calcium oxalate, uric acid, struvite, and cystine. A kidney stone may be treated with shockwave lithotripsy, uteroscopy, percutaneous nephrolithomy or nephrolithotripsy. Common symptoms include severe pain in lower back, blood in your urine, nausea, vomiting, fever and chills, or urine that smells bad or looks cloudy.

Urine has various wastes dissolved in it. When there is too much waste in too little liquid, crystals begin to form. The crystals attract other elements and join together to form a solid that will get larger unless it is passed out of the body with the urine. Usually, these chemicals are eliminated in the urine by the body's master chemist: the kidney. In most people, having enough liquid washes them out or other chemicals in urine stop a stone from forming. The stone-forming chemicals are calcium, oxalate, urate, cystine, xanthine, and phosphate.

Symptoms

Some kidney stones are as small as a grain of sand. Others are as large as a pebble. A few are as large as a golf ball! As a general rule, the larger the stone, the more noticeable are the symptoms.

The symptoms could be one or more of the following:

·         severe pain on either side of your lower back

·         more vague pain or stomach ache that doesn't go away

·         blood in the urine

·         nausea or vomiting

·         fever and chills

·        Urine that smells bad or looks cloudy

The kidney stone starts to hurt when it causes irritation or blockage. This builds rapidly to extreme pain. In most cases, kidney stones pass without causing damage-but usually not without causing a lot of pain. Pain relievers may be the only treatment needed for small stones. Other treatment may be needed, especially for those stones that cause lasting symptoms or other complications. In severe cases, however, surgery may be required.

How common are kidney stones?

Each year, more than half a million people go to emergency rooms for kidney stone problems. It is estimated that one in ten people will have a kidney stone at some time in their lives.

The prevalence of kidney stones in the United States increased from 3.8% in the late 1970s to 8.8% in the late 2020s. The prevalence of kidney stones was 30% The risk of kidney stones is about 27% in men and 16% in women. Other diseases such as high blood pressure, diabetes, and obesity may increase the risk for kidney stones.

What are the Causes

Possible causes include drinking too little water, exercise (too much or too little), obesity, weight loss surgery, or eating food with too much salt or sugar. Infections and family history might be important in some people. Eating too much fructose correlates with increasing risk of developing a kidney stone. Fructose can be found in table sugar and high fructose corn syrup.

The causes of kidney stones include inadequate water intake, irregular exercise (either excessive or insufficient), obesity, weight loss surgery, and diets high in salt or sugar. Additionally, family history and infections can play significant roles for some individuals. A notable correlation exists between high fructose consumption—found in table sugar and high fructose corn syrup—and an increased risk of developing kidney stones.

Types of stones:

There are four main types of

Calcium oxalate: The most common type of kidney stone which is created when calcium combines with oxalate in the urine. Inadequate calcium and fluid intake, as well other conditions, may contribute to their formation.

Uric acid: This is another common type of kidney stone. Foods such as organ meats and shellfish have high concentrations of a natural chemical compound known as purines. High purine intake leads to a higher production of monosodium urate, which, under the right conditions, may form stones in the kidneys. The formation of these types of stones tends to run in families.

Struvite: These stones are less common and are caused by infections in the upper urinary tract.

Cystine: These stones are rare and tend to run in families. What are Cystine Stones?

Treatment

Treatment for kidney stones is similar for both children and adults, often starting with an increased intake of water to encourage the stone to pass naturally. Doctors typically prefer to avoid surgery, and may prescribe medication to reduce urine acidity. However, if a stone is too large, obstructs urine flow, or indicates infection, surgical intervention may be necessary. Noninvasive shock-wave lithotripsy uses high-energy sound waves to break the stones into smaller fragments for easier passage. Ureteroscopy involves inserting an endoscope through the ureter to retrieve or destroy the stone, while percutaneous nephrolithotomy or nephrolithotripsy may be employed for larger or more complicated stones.

Why do doctors examine the contents of thestone?

There are four main types of kidney stones, and analyzing them can provide insight into their formation and how to mitigate the risk of recurrence. The most prevalent type is calcium stones, which are typically a result of excess calcium buildup combining with waste products like oxalate, leading to the formation of calcium oxalate stones. While calcium is a natural part of a healthy diet, individuals with stones often retain too much calcium. Other less common stones include struvite stones, formed from magnesium and ammonia due to infections, and uric acid stones, which arise from monosodium urate crystals and may be linked to obesity and dietary habits. The rarest variety, cystine stones, tend to have a hereditary component.

Prevention

To prevent kidney stones, it's crucial to stay well-hydrated by drinking enough fluids, primarily water, aiming for more than 12 glasses a day; your urine should be light yellow to clear. Limit consumption of sugary drinks and manage hydration levels during exercise or hot weather. Incorporating more fruits and vegetables helps produce less acidic urine, reducing stone formation risk, while limiting animal protein can further aid prevention. Reducing excess salt is essential, as many processed foods, like sandwich meats and canned soups, contain high sodium levels. If you're overweight, achieving a healthy weight is important, but avoid high-protein, crash diets that can increase stone risk; consult a registered dietitian for tailored dietary advice. Despite concerns about calcium stones, consuming dairy actually helps prevent them by binding oxalate, so adequate dietary calcium is beneficial. While some herbs claim to prevent stones, there is insufficient evidence supporting their effectiveness. If you've had a stone or are at risk, consult a healthcare professional to discuss dietary changes based on your medical history and eating habits. 


 Consult  wellsun  medicity discuss your risk factors and develop a personalized plan to reduce your risk.

Wellsun Medicity Multispecialty Hospital

www.wellsunmedicity.com

Dr. Neeraj Agarwal

MBBS (KGMU) MS General Surgeon

M.ch Urologist, Kidney Transplant Surgery   

Call:  +91-8810787432

Wednesday, October 30, 2024

wellsun-medicity-multispecialty hospital -Lucknow

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