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Recurrent pregnancy loss | Nature Reviews Disease Primers-Wellsun Medicity Hospital

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  Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more consecutive miscarriages prior to 20 weeks of gestation. It can result from various factors, including genetic, anatomical, hormonal, autoimmune, or chromosomal abnormalities, and can cause significant emotional distress for affected individuals. Evaluating the underlying causes is crucial for managing RPL and improving the chances of a successful pregnancy in the future. What causes recurrent pregnancy loss? Recurrent pregnancy loss can be caused by a variety of factors, including genetic abnormalities in either parent, anatomical issues such as uterine abnormalities or scarring, hormonal imbalances (like thyroid disorders or polycystic ovary syndrome), autoimmune conditions (such as antiphospholipid syndrome), and infections. Additionally, lifestyle factors, maternal age, and certain chronic health conditions can also contribute to the risk of miscarriage. Identifying the specific cause in each case is...